Dr. Yokoyama has been a member of the 好色先生 faculty since 2001.

Fall 2024 Office Hours
Mon 2:00p-4:00p
Tues 2:00p-4:00p
Thurs 2:00p-4:00p
Fri 2:00p-4:00p
or by appointment
Curriculum Vitae
Education
B.S. & M.S. University of Kobe, Japan (with Professor Hajime Kato)
Ph.D. University of Colorado (with Professor Carl Lineberger)
Post-Doctoral Fellow at University of Minnesota (with Professor Paul Barbara)
Publications: Papers
K. Yokoyama, E. Barbour, R. Hirschkind, Bryan Martinez Hernandez, K. Hausrath, and Theresa Lam
鈥淧rotein Corona Formation and Aggregation Process of Amyloid beta 1-40 Coated Gold Nano-Colloids鈥, Langmuir, Vol. 40, pp. 1728-1746 (2024).K. Yokoyama, J. Thomas, W. Ardner, M. Kieft, L. Neuwirth, and W. Lieu, 鈥淎n Approach for In Situ Detection of Amyloid Formations within the Hippocampus of the Cohen鈥檚 Alzheimer鈥檚 Disease Rat Model by Surface Enhanced Raman Scattering Methods鈥, Journal of Neuroscience Methods, Vol. 393 pp. 109892 - 109901 (2023)
K. Yokoyama and A. Ichiki, 鈥淎dsorption of Amyloidogenic Peptides at Nano-Scale Interface Studied by Spectroscopic Approach鈥, Journal of Visualized Experiments (under the review).
K. Yokoyama, T. Lam, J. Santariello, and A. Ichiki, 鈥淣ano-size dependent Reversible Self-assembly of SARS-CoV-2 Omicron Spike protein鈥, Colloids and Surfaces A, Volume 647 128967 - 128973 (2022)
K. Yokoyama and A. Ichiki, 鈥淎 Model for Nano-Scale Spherical Surface Coverage and Protein Corona Formation by Amyloidogenic Peptides , The International Journal of Biocomputing and Nano Technology Volume 1, pp. 21 鈥 28 (2022)
K. Yokoyama and A. Ichiki
"Nano-size Dependence in the Adsorption by the SARS-CoV-2 Spike Protein over Gold Colloid"
[Colloid and Surfaces A,Volume 615, pp. 126275-126281 (2021)K. Yokoyama and A. Ichiki, "Nano-Size Dependence in the Adsorption by the SARS-CoV-2 Spike Protein over Gold Colloid", Colloids and Surfaces A, Vol. 40 pp. 100356-100362 (2021)
K. Yokoyama and A. Ichiki, 鈥淲hat can peptide-coated nanoparticles tell us about the causes of dementia?鈥, Research OutreachJournal of Visualized Experiments, pp. 110-113, Issue 116 (2020)
K. Yokoyama, K. Brown, P. Shevlin, J. Jenkins, E. D'Ambrosio, N. Ralbovsky, J. Battaglia, I. Deshmukh, and A. Ichiki, 鈥淓xamination of Adsorption Orientation of Amyloidogenic Peptides Over Nano-Gold Colloidal Particles鈥 Surfaces鈥, Int. J. Mol. Sci., Vol 20, pp. 5354-5380 (2019).
K. Yokoyama, H. Chen, A. Islam, I. Deshmukh, P. Shevlin, K. Brown, and A. Ichiki, "Dynamical Investigation of Adsorption Orientation of Amyloid Beta Peptide 1-40 at Nano-Scale Gold Surface鈥, BAOJ Chemistry, Vol. 5 (1), pp. 1-20 (2019).
Publications: Text Book & Book Chapters
[TEXT BOOKS]
K. Yokoyama 鈥淢odern Physical Chemistry for Bioscience Students - Friendly and Short Cut Guide for Physical Chemistry鈥 (2011) Linus Publication, ISBN# 1-60797-185-2 First Edition (604 pages), ISBN# 1-60797-246-8 Second Edition.(618 pages), ISBN# 1-60797-337-5 Third Edition.(592 pages), ISBN978-1-60797-897-8 (2020)K. Yokoyama (Editor) 鈥淔rontiers in Nanoscience for Biomedical Research鈥 Research Signpost, ISBN# 978-81-308-0537-5, (2014).
[Book Chapters]
K. Yokoyama, 鈥淚nvestigation of protein-protein interaction utilizing nano-gold colloid surface plasmon resonance: Application to SARS CoV-2 spike protein coated gold colloids鈥, ACS Symposium Series Volume 1428, Physical Chemistry Research at Undergraduate Institutions 鈥 Innovative and impactful approaches Volume 2, Chapter 9 pp. 145-164, (2023) Edited by Todd Hopkins and Carol Parish, ISBN 978-0-8412-9743-2.Kazushige Yokoyama, Kieran Brown, Peter Shevlin, Jack Jenkins, Elizabeth D鈥橝mbrosio, Nicole Ralbovsky, Jessica Battaglia, Ishan Deshmukh and Akane Ichiki, "Examination of Adsorption Orientation of Amyloidogenic Peptides Over Nano-Gold Colloidal Particle Surfaces" pp. 75-102 in " Designer Biopolymers Self-Assembling Proteins and Nucleic Acids " Edited by Ayae Sugawara-Narutaki Yukiko Kamiya MDPI, Basel, Switzerland (2020)
ISBN 978-3-03936-370-4
K. Yokoyama and A. Ichiki "Chapter 3: Oligomerization and Adsorption Orientation of Amyloidogenic Peptides over Nano-Gold Colloidal Particle Surfaces鈥 pp. 139-194 in Advances in Chemical Research, Ed. by James C. Taylor, Nova Science Publishing, Hauppauge, NY, USA. (2020) ISBN: 978-1-53617-627-8.
K. Yokoyama, K. Brown, P. Shevlin, J. Jenkins, E. D鈥橝mbrosio, N. Ralbovsky, J. Battaglia, I. Deshmukh and Akane Ichiki, 鈥淓xamination of Adsorption Orientation of Amyloidogenic Peptides Over Nano-Gold Colloidal Particle Surfaces鈥, e-Book Book Chapter, Prime Archives in Molecular Biology, VideLeaf.
Kazushige Yokoyama 鈥淐ontrolling Reversible Self Assembly Path of Amyloid Beta Peptide over Gold Colloidal nanoparticle鈥檚 Surface鈥 Book Chapter in 鈥淣anoscale Spectroscopy with Applications鈥 Sarhan M. Musa 鈥揈d (CRC Press-Taylor and Francis Group, LLC) ISBN# 9781466568532 (2013) []
Kazushige Yokoyama 鈥淣ano Size Dependent Properties of Colloidal Surfaces鈥 Book Chapter in 鈥淐olloids: Classification, Properties and Applications鈥 (Nova Science Publishing) (2012)
Media Related
ACS Chemical Engineering News 鈥 Pictures in Chemistry (November, 2022)
White light image of Amyloid beta 12-28 coated Gold colloid aggregates
()Science Animation
YouTube "How do fibrils form?"
Yokovid Project "好色先生 Community Outreach through Science of COVID-19"
YouTube
Pod-Cast "Dimentia, degeneration, and gold nanoparticles"
Research Outreach (Science Magazine)
Kazushige Yokoyama & Akane Ichiki
"What can peptide-coated nanoparticles tell us about the causes of dementia?"
Issue 116 (pp. 110-113)
COVID Information Commons (CIC) Webinar: Winter 2024 Research Lightning Talks and Q & A
K. Yokoyama 鈥滻nvestigating Reversible Aggregation of SARS-CoV-2 Spike Protein-Coated Gold Colloid鈥
Journal Editorial Role
Guest Editor: MDPI-"Surfaces" Special Issue
Editorial Board Member of
Textbooks/Media
K. Yokoyama (Editor) 鈥淔rontiers in Nanoscience for Biomedical Research鈥 Research Signpost, ISBN# 978-81-308-0537-5, (2014)
K. Yokoyama
Friendly and Short Cut Guide for Physical Chemistry
Modern Physical Chemistry for Bioscience Students
(4th edition) Linus Learning ISBN978-1-60797-897-8 (2020)
[]
Problemset
Modern Physical Chemistry for Bioscience Students
Linus Learning (2021) ISBN 978-1-60797-931-9
Media (YouTube/iPod)
- Science behind COVID-19 (Community Outreach Project)
Brochure & You Tube - Podcast: ResearchPod 鈥淒ementia, degeneration, and gold nanoparticles鈥 (2019)
- Video Abstract 鈥淣anoparticles and dementia: understanding the role of fibrils鈥 (2019)
- Research Outreach 鈥淲hat can peptide-coated nanoparticles tell us about?鈥 Issue No. 116, pp. 110-113 (2020). (Research Outreach Featured Article page: )
- Science Animation 鈥淗ow do fibrils form?鈥 (2020)
- Yokoyama, K., Thomas, J., Ardner, W., Neuwirth, L.S. & Liu, W. Method for in situ detection of amyloid formation in the hippocampus of the Cohen's Alzheimer's disease rat model by Surface Enhanced Raman Scattering. in SSRN (, 2022).
Classes
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CHEM 290: Chemistry Research
This course provides an opportunity for students to engage in an exploratory laboratory research experience with a Chemistry Department faculty member. Research positions are arranged by consultation with the course instructor, faculty mentor, and student. A learning agreement and permission of instructor is required for class registration; use the link in section notes to submit a permission request.
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CHEM 324: Principles of Physical Chem
A foundational course surveying major topics in physical chemistry. Topics include gas laws, laws of thermodynamics, chemical and physical equilibria, chemical and enzyme kinetics, introductory quantum mechanics, and spectroscopy.
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CHEM 361: Physical Chemistry Lab
An introduction to, and application of a variety of physico, electro and spectro-chemical techniques currently used for the determination of physical and molecular properties and for chemical analysis. Use of modern instrumentation, including computerized data analysis, will be stressed.
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CHEM 490: Advanced Chemistry Research
An individual, student-led, advanced laboratory research experience with a Chemistry Department faculty member. Working with a faculty mentor, students design, perform, and analyze the results of a laboratory experiment. Students submit a written laboratory report that conforms to American Chemical Society Guidelines and a self-reflection about their experience. A learning agreement and permission of instructor is required for class registration. Use the link in section notes to submit a permission request.